What is the purpose of nitrates in the treatment of angina?

The purpose of nitrates in the treatment of angina is to increase blood flow by dilating blood vessels. Nitrates work primarily by relaxing and widening the blood vessels, which allows more blood to flow through them. This is particularly beneficial in angina, where the heart muscle does not get enough blood (and thus oxygen) during periods of stress or exertion. By reducing the workload on the heart and improving oxygen delivery to the heart muscle, nitrates help alleviate the pain associated with angina.

This mechanism addresses the underlying issue of restricted blood flow due to narrowed or obstructed coronary arteries, making nitrates a crucial component in managing angina symptoms effectively.